Wingers David Fusitu’a and Ash Handley are injured, along with Morgan Gannon and his fellow second-row Rhyse Martin is suspended.
There are doubts over scrum-half Aidan Sezer (knee) and prop Mikolaj Oledzki (knee) and coach Rohan Smith will have to decide whether to take a risk on players carrying knocks.
While the back line seems straight-forward, the pack is more of an issue. Here’s a predicted lineup.
1. Full-back: Richie Myler
If Aidan Sezer is ruled out, he'll probably shift into the halves, otherwise set to continue at full-back. Photo: Will Palmer/SWpix.com
2. Wing: Liam Tindall
With Rhinos two wingers down, the rookie is set for the biggest game of his career. Photo: Bruce Rollinson
3. Centre: Zak Hardaker
Will no doubt receive a warm welcome at his previous home ground. Photo: Allan McKenzie/SWpix.com
4. Centre: Liam Sutcliffe
Hat-trick hero at Catalans, will want to extend his time at Rhinos into a final week. Picture by Manuel Blondeau/SWpix.com. Photo: Manuel Blondeau/SWpix.com
5. Wing: Tom Briscoe
With Rhinos short on wingers, the veteran's experience will be crucial. Photo: Manuel Blondeau/SWpix.com
6. Stand-off: Blake Austin
One of Rhinos' strike players and has been in good form since returning from injury. Photo: Allan McKenzie/SWpix.com